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My memory is not sharp at my age. I also take Aspirin, Metformin 500mg, Lansoprazole 30mg and Atorvastatin 20mg.

May 7
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MyHeartDiseaseTeam

Are over-the-counter brain health supplements safe to take alongside CHF medications like Entresto and Carvedilol?

This is such an important question, and it's great that you're thinking carefully before adding anything new to your routine — especially with the medications you're already managing.

With CHF, the heart Show Full Answer

Are over-the-counter brain health supplements safe to take alongside CHF medications like Entresto and Carvedilol?

This is such an important question, and it's great that you're thinking carefully before adding anything new to your routine — especially with the medications you're already managing.

With CHF, the heart isn't pumping as efficiently as it should, and this can actually contribute to reduced blood flow to the brain, which may affect memory and mental sharpness. So your concern is very valid and worth discussing with your cardiologist. The tricky part with OTC brain health supplements is that many haven't been well-studied alongside heart medications. Some key concerns include:

- Blood thinning effects — Some supplements (like ginkgo biloba or fish oil) can thin the blood, which may be risky when combined with aspirin
- Blood pressure interactions — Certain herbal ingredients can raise or lower blood pressure, interfering with Carvedilol
- Heart rhythm effects — Some stimulant-based supplements can affect heart rate, which is a concern with CHF

Given your current medication list, it's really important to check with your cardiologist or pharmacist before adding anything new — even if it's labeled "natural." They can review potential interactions specific to your situation and help find a safe option if one exists.

May 7
A MyHeartDiseaseTeam Member

Hi Gwen,

I am on Carvedilol, Entresto, Farxiga, and Spironolactone (GDMT for heart failure) without such an issue. Am not familiar with the side effects of your other meds, but the statin might be worth looking into.

Also, just noticed in a following thread that in June your cardiologist drastically increased your dosage of Carvedilol. One of the major side effects of excess Carvedilol is brain fog. (You could be getting "a double whammy" from the statin and the excess Carvedilol.) - No, you are not imagining things!

You should definitely consult with a pharamacist, your cardiologist, and/or get second opinions to see if you can get the cognitive issues under control, and not just take it as an inevitable side effect of your drug regimen.

Praying for the best!

August 26 (edited)
A MyHeartDiseaseTeam Member

Gwen3
I haven’t tried any of them. I have a subscription to Consumerlab.com and they have nothing good to say about those products in a positive way. My neurologist has recommended some medication for my mild cognitive impairment but after researching them on worstpills.org and the side effects I am going to pass on using them. Wish you all the best

May 12
A MyHeartDiseaseTeam Member

I have tried Prevagen, and Neuriva (I think that is the name of it). I found neither one helped me But the reason I started with them, they may not be designed to work on that.

May 7
A MyHeartDiseaseTeam Member

Thanks Tony,❤️ I checked with my Cardiologist first for me. Good Advice.

June 4

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Los Angeles, CA