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Peripheral artery disease (PAD) can cause artery clogging in areas outside the heart, such as the arms, legs, stomach, or head. It most commonly affects the arteries in the legs, leading to blockages that prevent tissues from receiving blood. This can result in intense pain, tissue death (gangrene), stroke, or brain damage Show Full Answer

Peripheral artery disease (PAD) can cause artery clogging in areas outside the heart, such as the arms, legs, stomach, or head. It most commonly affects the arteries in the legs, leading to blockages that prevent tissues from receiving blood. This can result in intense pain, tissue death (gangrene), stroke, or brain damage, especially if it develops in the head or neck arteries.

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