Nexletol (Bempedoic acid) for Heart Disease | MyHeartDiseaseTeam

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Nexletol is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat adults with heterozygous familial hypercholesterolemia or established atherosclerotic cardiovascular disease who require additional lowering of low-density lipoprotein cholesterol (LDL-C). Nexletol is indicated as an adjunct therapy to diet and maximally-tolerated statin therapy. Nexletol is also referred to by its drug name, bempedoic acid.

Nexletol is a member of the adenosine triphosphate-citrate lyase (ACL) inhibitor class of drugs. It is believed to work in cases of heart disease by inhibiting cholesterol production in the liver. This lowers the levels of LDL-C in the bloodstream.

How do I take it?
Prescribing information states that Nexletol is taken orally as a tablet once daily.

Side effects
The FDA-approved label for Nexletol lists common side effects including respiratory tract infection, muscle spasms, high blood uric acid levels, back pain, abdominal pain, bronchitis, low blood cell counts, and elevated liver enzymes.

A rare but serious side effect listed for Nexletol is tendon rupture.

Nexletol may cause adverse reactions when combined with certain other medications. Inform your doctor of any medications you take and any existing medical conditions before taking Nexletol.

For more details about this treatment, visit:

Nexletol — Esperion

Nexletol —

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