So true Elaine, I have been on Entresto for about a year and a half; my EF was at one point just 15 percent, it is now 25-30%, but it can drop at any point, I sometimes day dream of days when there were no heart problems. To hear of dementia chances is even more worrisome. Will have another echo very soon.

I was recently put on entresto. I can ask my Dr on Monday. I'll let you know what he says

Hi, Everyone!! Yes, I have been on Entresto for 3 years! I was put on the lowest dose at first and then started taking the middle Dose! It did raise my EF to 40 from a low of 25%! The middle dose lowered my Blood Pressure to a dangerous level! My cardiologist recommended a pacemaker with a defibrillator! I had the surgery 7 weeks ago ! I feel wonderful now! I also take the lowest dose of Entresto again and 25 mg of Metropolo twice a day!!

Thank you, I hope the study results is good news, for the drug does help a lot of people.

According to my doctor, the possibility of that happening is very low. He didn't give me a percentage. He said it had to do with family history. Hope this helps.